Our Board

At Oncode Institute, our mission is guided and protected by a dedicated group of boards and committees. Together, they bring expertise, oversight and vision - helping us accelerate progress in cancer research, ensure responsible management of funds, and serve society with integrity and impact.

Our Governance 

Oncode Institute operates with a lean, skilled team that provides support and valorisation services to researchers at our partner institutions. While our staff does not conduct research directly, they work side by side with our boards and committees to foster collaboration, uphold strong governance and drive continuous improvement across the organisation.

We are committed to transparency, accountability and good governance. Our Good Governance Charter is rooted in the Dutch Corporate Governance Code and the SBF Good Governance Code for charities.

Everyone connected to Oncode Institute - staff, researchers, partners and patients - plays a role in shaping our future. By listening to diverse voices, we make better decisions that ultimately benefit all.

We welcome your questions and suggestions, and invite you to contact us.

Our Boards and Committees

Supervisory Board 

The Supervisory Board oversees the Managing Board and the overall operations and governance of Oncode Institute. It monitors strategic direction, risk management, financial health and compliance with legislation - ensuring alignment with our mission. Above all, it safeguards Oncode Institute’s integrity, continuity and public purpose.

Name

Melvin Samsom

Position
Chair

Melvin Samsom is a Professor of Gastroenterology at Radboudumc. He is also Senior Advisor at KPMG Health, Non-Executive Director of the Group Board of Bupa, in London, and Chair of the Supervisory Committee Reorganization Academic Care Landscape for the Dutch Ministry of Health, Welfare and Sport. He has held various management positions within Radboudumc and also acted as CEO of Karolinska University Hospital.

Name

René Kuijten

Position
Vice-chair

René Kuijten is one of the initiators of Oncode Institute and is partner and Head of EQT Life Sciences (previousy LSP) within EQT, a global private equity and venture capital investment firm. After his training as a physician in Utrecht he obtained a PhD degree as a WHO fellow, based on cancer research performed at the University of Pennsylvania. He received his MBA from INSEAD and was a consultant at McKinsey & Co. in Amsterdam, Zurich and Brussels from 1992-2000, a.o. leading their healthcare practice. In 2001 he joined LSP (now EQT Life Sciences) and has founded and supported many life science companies. René also serves as a member of the steering committee in the Dutch Topsector Life Science & Health, is on the advisory board of health care insurer Menzis, and on the advisory board of Utrecht Life Sciences, University of Utrecht.

Name

Ben Feringa

Position
Supervisory Board

Ben Feringa is Jacobus van ‘t Hoff Distinguished Professor of Molecular Sciences at the University of Groningen. His research interest includes stereochemistry, organic synthesis, asymmetric catalysis, molecular switches and motors, self-assembly, molecular nanosystems and photopharmacology. He received the 2016 Nobel Prize in chemistry and was knighted by Her Majesty the Queen of the Netherlands in 2008. He is Board Member of the Royal Netherlands Academy of Sciences (KNAW), Chairman Board Chemistry Division of the Netherlands Science Foundation NWOCW among many other involvements.

Name

Edvard Beem

Position
Supervisory Board

Until 2017, Edvard Beem has served as co-director of The Netherlands Organisation for Health Research and Development (ZonMw). Since its establishment in 2001, he was responsible for research strategy, public-private co-operation and international relations at ZonMw. Edvard was originally trained as a biochemist and spend most of his scientific career at the Netherlands Cancer Institute. He also serves as the chair of the General Assembly of Joint Programming Initiative “More Years, Better Lives” and held governmental positions in numerous international funding consortia promoting European and global collaboration in research, innovation and infrastructures.

Name

Fred Falkenburg

Position
Supervisory Board
Name

Tanja Nagel

Position
Supervisory Board

Tanja Nagel has had a long career in the financial sector. In 2009 she became CEO at Theodoor Gillissen Bankers, a position she held until 2017. During her career she has gained ample experience in supervising diverse organisations and companies. Amongst others, she served on the supervisory boards of the Pink Ribbon Foundation and The National Maritime Museum and chaired the audit committee in both boards. Next to her role at Oncode, she currently serves in in the board of the Utrecht University Fund and in the supervisory boards of PNO consultants and EY The Netherlands.

Name

Stefan Sleijfer

Position
Supvervisory Board
Name

Dianda Veldman

Position
Supervisory Board

Management Board

The Management Board leads Oncode Institute with a strong sense of social responsibility. Responsible for the day-to-day operation and management of the institute, it consists of our Scientific Director and Managing Director.

Name

Jan Paul Medema

Position
Scientific Director

Jan Paul Medema is Scientific and chair of the Research Management Committee of Oncode Institute. He is also group leader at Amsterdam University Medical Centers and Professor Experimental Oncology and Radiobiology at the University of Amsterdam. His group studies the biology and therapy of colorectal cancer from a heterogeneity point of view considering both the intra tumor heterogeneity that is defined by a CSC hierarchy as well as by clonal evolution and inter-tumor heterogeneity, which is defined by distinct subtypes as well as mutation profiles.

Bertholt_Leeftink_Joins_Oncode_Institute
Name

Bertholt Leeftink

Position
Managing Director

Bertholt Leeftink is the Managing Director of Oncode Institute, responsible for strategy, governance, and valorization at Oncode Institute — three core areas essential to shaping the organisation’s future. His appointment reflects Oncode’s ambition to further integrate science and impact in the years ahead. Leeftink brings a proven track record at the intersection of government, innovation, and business.

He previously served as CEO of NRG PALLAS, a global leader in the production of medical isotopes (2019–2024), and was Director-General for Enterprise and Innovation at the Ministry of Economic Affairs and Climate Policy. In this role, he played an instrumental part in the founding of Oncode Institute in 2017. Leeftink is a strong advocate for public-private partnerships, has been closely involved in creating Invest-NL, and brings broad experience across the life sciences sector and beyond. He holds a PhD in economics from the University of Amsterdam.

Management Team

Our Management Team provides strategic and operational guidance, ensuring our goals are translated into meaningful action across the organisation.

Name

Ester Frische

Position
Head of Research and Community

Ester is a biomedical scientist by training with experience in both an academic and a biotech environment. She obtained her PhD in the lab of Hans Bos at the UMC Utrecht. She studied signalling routes in cancer biology and continued this line of research at Galapagos in Leiden. In 2010 Ester moved into scientific project management and is managing director of CancerGenomics.nl since 2015. She has been involved with Oncode Institute since its early days and supported the founders in developing the scientific strategy. In her current role as Programme Manager, Ester supports the Scientific Director and Research Management Committee and is responsible for all programmes directly related to supporting research and the link to the clinic. This includes managing dedicated funds for clinical proof of concept projects and large equipment and technology applications.

Name

Veerle Fleskens

Position
Head of Strategy & Stakeholder Management

Veerle is a molecular biologist by training, specialized in molecular immunology. She obtained her PhD from Utrecht University at the University Medical Center Utrecht, followed by postdoctoral research at King’s College London. After several years as a life sciences and business consultant, she joined Oncode Institute as Business Development Manager. Here she supports Oncode Investigators to develop valorization strategies and translate their scientific findings to truly benefit society. Furthermore, she uses her expertise to initiate public-private partnerships and provide support for funding applications to all Oncode Researchers.

Research Management Committee 

The Research Management Committee (RMC) provides guidance and advises the Managing Board on all research related matters, including scientific strategy, selection of Oncode Investigators, scientific monitoring and building Oncode Institute’s research community. Oncode Investigators and the chair of the Clinical Advisory Board form the RMC, with the Scientific Director serving as chair.

Name

Jan Paul Medema

Position
Scientific Director

Jan Paul Medema is Scientific and chair of the Research Management Committee of Oncode Institute. He is also group leader at Amsterdam University Medical Centers and Professor Experimental Oncology and Radiobiology at the University of Amsterdam. His group studies the biology and therapy of colorectal cancer from a heterogeneity point of view considering both the intra tumor heterogeneity that is defined by a CSC hierarchy as well as by clonal evolution and inter-tumor heterogeneity, which is defined by distinct subtypes as well as mutation profiles.

Name

Henk Verheul

Position
Erasmus MC (Chair CAB)
Name

Marvin Tanenbaum

Position
Oncode Investigator at Hubrecht Institute and Professor in the department of Bionanoscience at the TU Delft

Clinical Advisory Board 

The Clinical Advisory Board (CAB) provides guidance and advises the RMC and Managing Board on clinical research related themes, including strategy, clinical projects and allocation of funds within the clinical proof-of-concept programme. Upon request, the CAB provides advice to Oncode Investigators on the clinical development of their research. Members are clinical professionals and patient representatives. Its chair is also a member of the RMC.

Name

Henk Verheul

Position
Erasmus MC (Chair CAB)
Name

Natasha van Eijkelenburg

Position
Princess Máxima Institute
Name

Ewout Steyerberg

Position
LUMC
Name

Ferry Eskens

Position
Eramsus MC
Name

Jeanine Roodhart

Position
UMC Utrecht
Name

Muriëlle Sark

Position
Patient Representative
Name

Lianne Bogers

Position
Patient Representative
Name

André Bergman

Position
NKI
Name

Sjoukje Oosting

Position
UMCG

International Advisory Board 

The International Advisory Board (IAB) provides strategic advice to the Managing Board and Supervisory Board. Its role is to review annually the progress in executing Oncode Institute’s strategy - focusing on scientific and valorisation objectives as outlined in the Strategic Plan. The IAB brings together leading experts from around the world to guide Oncode Institute’s future direction and offer informed advice.

Name

Teri Willey

Position
Pathway to Cures Venture Fund
Name

Richard Marais

Position
Paterson Institute and CRUK
Name

Vishva Dixit

Position
Genentech
Name

Clare Isacke

Position
ICR London

Professor Clare Isacke studied Biochemistry and graduatedin Developmental Biology with John Heath at the University of Oxford. She then moved to Tony Hunter's laboratory at the Salk Institute in San Diego to work on growth factor receptor signalling as a postdoctoral fellow. On returning to England, she started her own research laboratory first in the Department of Biochemistry and then in the Department of Biology at Imperial College London. She was appointed Professor of Molecular Cell Biology in 2000. In 2001, Professor Isacke moved to The Institute of Cancer Research in London to take up an appointment as Professor of Molecular Cell Biology in the Breast Cancer Now Toby Robins Research Centre. Currently, she is Academic Dean at the ICR. Professor Isacke aims to identify the processes by which tumour cells recruit non-cancerous cells during metastasis.

Name

Alberto Bardelli

Position
Department of Oncology, University of Torino
Name

Sabine Tejpar

Position
UZ Leuven
Name

Paul Workman

Position
ICR, London

Professor Paul Workman is Harrap Professor of Pharmacology and Therapeutics at The Institute of Cancer Research (ICR) in London and is also a Group Leader in Signal Transduction and Molecular Pharmacology at ICR. From 2014-2021 he served as Chief Executive and President of the ICR and from 1997-2016 he was Director the ICR’s CRUK Cancer Therapeutics Unit. Paul previously held senior research positions at the MRC Oncology Unit, Cambridge University; CRUK Beatson Laboratories, Glasgow University; and Zeneca Pharmaceuticals, Alderley Park. Paul is an international leader in the field of cancer drug discovery and chemical biology, known especially for his work on the discovery of inhibitors of protein kinases, PI3 kinases, HSP90, HSP70 and the HSF1 and integrated stress response pathways.  He has been instrumental in the discovery of multiple molecular therapeutic agents that have entered clinical trials, including the approved drugs gefitinib and capivasertib. As a scientific entrepreneur, Paul has been involved in multiple biotech companies, including as Scientific Founder of Chroma Therapeutics and Piramed Pharma (acquired by Roche). An enthusiast for high-quality chemical probes in biomedical research, Paul is Executive Director of the non-profit Chemical Probes Portal. Paul has received multiple awards and fellowships and is a Fellow of the Royal Society (the UK’s academy of science).

Oncode Exploratory Development Expert Support (OEDES)

The OEDES team consists of independent experts who help translate fundamental scientific insights into new diagnostics and therapeutic strategies. They advise on the design of preclinical and clinical approaches, including defining product profiles, proof-of-concept criteria and identifying predictive biomarkers. With experience across leading pharmaceutical and innovative biotech companies, OEDES supports a broad spectrum of research areas.

Name

Ellen Hulskotte

Name

Danny Burg

Danny is a European Registered Toxicologist and has 20 years of experience in oncology drug development, which includes research positions at the Netherlands Cancer Institute and Leiden University, and several positions within the pharmaceutical industry. In 2018 he co-founded D2Team, a consultancy company that provides non-clinical development services for the pharma/biotech industry. His experience covers bioanalysis, drug metabolism and biomarkers, and nonclinical toxicology support for small molecules and biologicals in all phases of drug development.

Community Committee 

Representing the Oncode community, the Community Committee advises Oncode Institute on community-building activities and acts as a sounding board to staff. It also leads the organisation of activities for the Oncode community - including career and networking events - to strengthen and connect the community.

Members: Weixin Liao (Ten Dijke lab), Lesley Cornet (Akkari lab), Joao Fernandes Neto (Bernards lab), Menno Boon (Akkari lab), Martina Färber (Akkari lab), Konstantina Strepi (Jonkers lab), Margit Janssen (Michiel Vermeulen lab), Simon Venneman (Van Heesch lab), Carla Rios Arceo (Drost lab) and Iris Mimpen (Voest lab). 

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