Why Clinical Proof of Concept matters 

At Oncode Institute, we believe that promising innovations need the support to reach the clinic. Our Clinical Proof of Concept (CPoC) programme accelerates this journey by helping researchers test bold new ideas in early clinical studies – the critical step that shows whether an innovation truly has the potential to improve patient outcomes. Moving discoveries from the laboratory into real-world treatments is one of the toughest challenges in cancer research. Promising insights often stall before they reach patients, not because they lack potential, but because this vital first step in clinical testing is complex and resource-intensive. 

The CPoC programe bridges this gap. By combining targeted funding with expert support, we give researchers the tools and guidance to find out whether their idea can make a real difference for patients. 

Patient Involvement at the Core 

We believe patients can provide valuable insights into the patients’needs and relevance of new innovations. That is why we actively involve patient representatives in shaping and reviewing all proposals. Their voice ensures new treatments respond to real needs and that any potential burdens are carefully considered.

How It Works 

We invite researchers and clinicians to submit their most promising ideas for early-stage clinical studies. From the start, our experts work side by side with applicants: helping design proposals, define success criteria and bring in the right partners. 

Crucially, patients are involved from the very first step. Their insights help ensure that studies are meaningful, realistic and designed with their needs in mind. 

Real-World Impact 

The CPoC programe is already making a difference. We have supported projects that address some of the most pressing challenges in cancer care, such as: 

• Developing new treatment strategies for glioblastoma and melanoma
• Understanding why some patients respond to immunotherapy while others do not
• Advancing tools to match the right patient to the right treatment at the right time 

These are not just ideas on paper: they are steps towards better care for people living with cancer.