By Sebastian Gregoricchio (lab Wilbert Zwart, Netherlands Cancer Institute)  

In this masterclass, Sebastian Gregoricchio and invited speakers will introduce you to the principles of the Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq). This technique allows for the detection of accessible chromatin, which is not “protected” by nucleosomes and transcription factors. However, these data can be exploited to infer much more than mere chromatin accessibility. The masterclass will include both lectures on innovative analysis approaches and hands-on data practical for the most common quality controls and differential peak analyses. These technologies have applications in a broad range of biology fields. 

NOTE: Basic familiarity with R and shell/bash/terminal is required for the practical.  

Invited speakers 

Carlie de Vries (Amsterdam UMC) 
Luca Braccioli (Utrecht University) 
Aayush Grover (ETH Zürich, Switzerland – Valentina Boeva lab) 

Programme 

You can download the programme here.

Practical details 

Date: Friday September 19, 2025 
Time: 10:30 – 17.30 (with breaks) 
Location: Z4, NKI 

Target audience 

The entire Oncode Institute community. A limited number of spots are available for non-Oncode researchers. If you are an industry representative or a non-Oncode researcher and would like to join this masterclass, please contact Colette ten Hove first. Lectures will be given at a basic/entry level.

 
Registration 

Please register for the event here. 
Registration is limited to 35 participants, so please register as soon as possible. 

For further details, please contact the organising team.