The Protein A - TurboID - proximity biotinylation enzyme, developed by researchers at Radboud University and as published in Nature Communications, represents a significant advancement in the quest to understand cellular dynamics at the molecular level, including the profiling of interactomes. Unlike traditional methods that typically require CRISPR-based genetic manipulation or cellular transfection, this novel off-the-shelf approach harnesses the power of the TurboID enzyme coupled with Protein A, eliminating the need for complex genetic techniques. This streamlined process allows for rapid and efficient labelling of proteins and their surrounding environments within cells, providing researchers with invaluable insights into protein interactions and post-translational modifications.

The product offers researchers another tool to unravel the mysteries of cellular biology through interaction proteomic analysis of any cell type of interest. Through collaborative efforts and unwavering dedication to scientific excellence, Oncode Institute remains at the forefront of advancing fundamental science, particularly for cancer research and improving patient outcomes.