Our research is centered around the main question how to exploit the immune system to fight against cancer. Although immunotherapy has now successfully entered the clinic still a large number of patients do not benefit. Current research is focused on the design novel nanomedicines to more effectively activate the immune system  

Our primary work focusses on synthetic dendritic cells, mimicking natural antigen presenting dendritic cells.   Synthetic dendritic cells consist of polymer filaments on which antigens, cytokines and immunostimulants are adjoined by click chemistry techniques. These are designated ‘immunofilaments’ . We demonstrated that these not only can stimulate in vitro but also in vivo in preclinical mouse models