Louis Vermeulen MD PhD studied medicine at the University of Amsterdam. In 2010 he obtained his PhD (cum laude) on the topic of cancer stem cells in colorectal cancer. He spent several years at the Cancer Research UK institute in Cambridge as a postdoctoral Fellow. Louis trained as a medical oncologist and established his independent research group at the Cancer Center Amsterdam of the Amsterdam UMC. Currently he is Vice President and head of Discovery Oncology at Genentech inc., and professor of molecular oncology at the Amsterdam UMC – University of Amsterdam.

• NYSCF Robertson Stem Cell Investigator Award

• ERC Starting Grant (2015);ERC Consolidator Grant (2021)

• Vidi (2015) ;Vici (2021)

• Ammodo-KNAW Life Science Award

1. Molecular characterization of colorectal cancer related peritoneal metastatic disease.
   Lenos KJ, Bach S, Ferreira Moreno L, Ten Hoorn S, Sluiter NR, Bootsma S, Vieira Braga FA, Nijman LE, van den Bosch T, Miedema DM, van Dijk E, Ylstra B, Kulicke R, Davis FP, Stransky N, Smolen GA, Coebergh van den Braak RRJ, IJzermans JNM, Martens JWM, Hallam S, Beggs AD, Kops GJPL, Lansu N, Bastiaenen VP, Klaver CEL, Lecca MC, El Makrini K, Elbers CC, Dings MPG, van Noesel CJM, Medema JP, Koster J, Koens L, Punt CJA, Tanis PJ, de Hingh IH, Bijlsma MF, Tuynman JB, Vermeulen L.Nat Commun. 2022 Aug 4;13(1):4443. doi: 10.1038/s41467-022-32198-z.

2. Apc-mutant cells act as supercompetitors in intestinal tumour initiation.
   van Neerven SM, de Groot NE, Nijman LE, Scicluna BP, van Driel MS, Lecca MC, Warmerdam DO, Kakkar V, Moreno LF, Vieira Braga FA, Sanches DR, Ramesh P, Ten Hoorn S, Aelvoet AS, van Boxel MF, Koens L, Krawczyk PM, Koster J, Dekker E, Medema JP, Winton DJ, Bijlsma MF, Morrissey E, Léveillé N, Vermeulen L.Nature. 2021 Jun;594(7863):436-441. doi: 10.1038/s41586-021-03558-4. Epub 2021 Jun 2.

3. Continuous clonal labeling reveals uniform progenitor potential in the adult exocrine pancreas.
   Lodestijn SC, van den Bosch T, Nijman LE, Moreno LF, Schlingemann S, Sheraton VM, van Neerven SM, Koning JJ, Vieira Braga FA, Paauw NJ, Lecca MC, Lenos KJ, Morrissey E, Miedema DM, Winton DJ, Bijlsma MF, Vermeulen L.Cell Stem Cell. 2021 Nov 4;28(11):2009-2019.e4. doi: 10.1016/j.stem.2021.07.004. Epub 2021 Aug 5.

4. Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts.
   van der Heijden M, Miedema DM, Waclaw B, Veenstra VL, Lecca MC, Nijman LE, van Dijk E, van Neerven SM, Lodestijn SC, Lenos KJ, de Groot NE, Prasetyanti PR, Arricibita Varea A, Winton DJ, Medema JP, Morrissey E, Ylstra B, Nowak MA, Bijlsma MF, Vermeulen L.Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6140-6145. doi: 10.1073/pnas.1813417116. Epub 2019 Mar 8.

5. Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer.
   Lenos KJ, Miedema DM, Lodestijn SC, Nijman LE, van den Bosch T, Romero Ros X, Lourenço FC, Lecca MC, van der Heijden M, van Neerven SM, van Oort A, Leveille N, Adam RS, de Sousa E Melo F, Otten J, Veerman P, Hypolite G, Koens L, Lyons SK, Stassi G, Winton DJ, Medema JP, Morrissey E, Bijlsma MF, Vermeulen L.Nat Cell Biol. 2018 Oct;20(10):1193-1202. doi: 10.1038/s41556-018-0179-z. Epub 2018 Sep 3.